2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members
Por um escritor misterioso
Last updated 20 fevereiro 2025
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mRNA ageing shapes the Cap2 methylome in mammalian mRNA
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Evolution-guided functional analyses reveal diverse antiviral specificities encoded by IFIT1 genes in mammals
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Genes, Free Full-Text
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Regulation of antiviral innate immunity by chemical modification of viral RNA - Li - 2022 - WIREs RNA - Wiley Online Library
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Immune evasion of SARS-CoV-2 from interferon antiviral system - ScienceDirect
Full article: An epigenetic 'extreme makeover': the methylation of flaviviral RNA (and beyond)
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Attenuation of SARS‐CoV‐2 replication and associated inflammation by concomitant targeting of viral and host cap 2'‐O‐ribose methyltransferases
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2'-O-methylation of the second transcribed nucleotide within mRNA 5' cap impacts protein production level in a cell specific manner and contributes to RNA immune evasion
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2'-O-Methylation of the second transcribed nucleotide within the mRNA 5' cap impacts the protein production level in a cell-specific manner and contributes to RNA immune evasion. - Abstract - Europe PMC
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Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2′-O methylations
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Methylation of RNA Cap in SARS-CoV-2 captured by serial crystallography
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Messenger RNA Cap Methylation in Vesicular Stomatitis Virus, a Prototype of Non‐Segmented Negative‐Sense RNA Virus
2′-O Methylation of the Viral mRNA Cap by West Nile Virus Evades Ifit1-Dependent and -Independent Mechanisms of Host Restriction In Vivo
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Viruses, Free Full-Text
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Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5
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