2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members
Por um escritor misterioso
Last updated 04 janeiro 2025
mRNA ageing shapes the Cap2 methylome in mammalian mRNA
Evolution-guided functional analyses reveal diverse antiviral specificities encoded by IFIT1 genes in mammals
Genes, Free Full-Text
Regulation of antiviral innate immunity by chemical modification of viral RNA - Li - 2022 - WIREs RNA - Wiley Online Library
Immune evasion of SARS-CoV-2 from interferon antiviral system - ScienceDirect
Full article: An epigenetic 'extreme makeover': the methylation of flaviviral RNA (and beyond)
Attenuation of SARS‐CoV‐2 replication and associated inflammation by concomitant targeting of viral and host cap 2'‐O‐ribose methyltransferases
2'-O-methylation of the second transcribed nucleotide within mRNA 5' cap impacts protein production level in a cell specific manner and contributes to RNA immune evasion
2'-O-Methylation of the second transcribed nucleotide within the mRNA 5' cap impacts the protein production level in a cell-specific manner and contributes to RNA immune evasion. - Abstract - Europe PMC
Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2′-O methylations
Methylation of RNA Cap in SARS-CoV-2 captured by serial crystallography
Messenger RNA Cap Methylation in Vesicular Stomatitis Virus, a Prototype of Non‐Segmented Negative‐Sense RNA Virus
2′-O Methylation of the Viral mRNA Cap by West Nile Virus Evades Ifit1-Dependent and -Independent Mechanisms of Host Restriction In Vivo
Viruses, Free Full-Text
Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5
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