Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models
Por um escritor misterioso
Last updated 14 fevereiro 2025
![Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41467-018-08164-z/MediaObjects/41467_2018_8164_Fig1_HTML.png)
![Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models](https://www.biorxiv.org/content/biorxiv/early/2020/04/22/2020.04.22.053561/F5.large.jpg)
TBX3 acts as tissue-specific component of the Wnt/β-catenin
![Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models](https://ars.els-cdn.com/content/image/1-s2.0-S0300908422000190-gr1.jpg)
Wnt/β-catenin signaling in colorectal cancer: Is therapeutic
![Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41467-018-08164-z/MediaObjects/41467_2018_8164_Fig1_HTML.png)
Bcl9 and Pygo synergise downstream of Apc to effect intestinal
![Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models](https://www.researchgate.net/publication/43343461/figure/fig1/AS:214105685270528@1428058181735/A-Immunofluorescence-of-SW480-cells-for-total-b-catenin-or-ABC-active-b-catenin-Both.png)
A) Immunofluorescence of SW480 cells for total β-catenin or ABC
![Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41467-018-08164-z/MediaObjects/41467_2018_8164_Fig4_HTML.png)
Bcl9 and Pygo synergise downstream of Apc to effect intestinal
![Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fng1265/MediaObjects/41588_2003_Article_BFng1265_Fig1_HTML.jpg)
Colonic polyposis caused by mTOR-mediated chromosomal instability
![Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models](https://www.biorxiv.org/content/biorxiv/early/2022/06/12/2022.06.10.495115/F7.large.jpg)
β-catenin obstructs γδ T cell immunosurveillance in colon cancer
![Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41598-020-74080-2/MediaObjects/41598_2020_74080_Fig1_HTML.png)
Multivalent tumor suppressor adenomatous polyposis coli promotes
![Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models](https://www.biorxiv.org/content/biorxiv/early/2022/06/12/2022.06.10.495115/F9.large.jpg)
β-catenin obstructs γδ T cell immunosurveillance in colon cancer
![Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models](https://media.springernature.com/w136h75/springer-static/image/art%3A10.1038%2Fs41418-021-00816-w/MediaObjects/41418_2021_816_Fig1_HTML.png)
Bcl9 and Pygo synergise downstream of Apc to effect intestinal
![Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models](https://www2.mrc-lmb.cam.ac.uk/groups/bienz/wp-content/uploads/sites/23/Slide4-2.jpg)
Pygo and BCL9: the Wnt enhanceosome
New ZW4864 Derivatives as Small-Molecule Inhibitors for the β
![Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41467-023-39439-9/MediaObjects/41467_2023_39439_Fig2_HTML.png)
Structural basis of the interaction between BCL9-Pygo and LDB-SSBP
![Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models](https://iiif.elifesciences.org/lax/58123%2Felife-58123-fig2-figsupp1-v1.tif/full/full/0/default.jpg)
TBX3 acts as tissue-specific component of the Wnt/β-catenin
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