Assessment of neuroendocrine dysfunction following traumatic brain injury.
Por um escritor misterioso
Last updated 18 fevereiro 2025
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A screening protocol adapted for selected patients at risk for endocrine problems is described, and physicians should be aware of the importance of neuroendocrine dysfunction following TBI. Posttraumatic neuroendocrine pathology may be a clinically significant complication following traumatic brain injury TBI. Metabolic abnormalities are described after TBI in two cases. A 21 year old male injured in a motor vehicle accident admitted in a minimally responsive condition presented with fluctuating high sodium levels, undetectable serum testosterone, and depressed cortisol and thyroid function. Imaging revealed near complete avulsion of the pituitary stalk leading to panhypopituitarism. A 38 year old male admitted for occipital skull fractures and brain contusions presented with hypona tremia and low serum testosterone. Both patients required hormonal replacement and correction of electrolyte abnormalities. A screening protocol adapted for selected patients at risk for endocrine problems is described. While neuroendocrine screening is not advocated in all TBI patients, physicians should be aware of the importance of neuroendocrine dysfunction following TBI.
TBI Resources for Medical Providers
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Neuroendocrine Dysfunction in the Acute Setting of Penetrating Brain Injury: A Systematic Review - ScienceDirect
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Assessment of neuroendocrine dysfunction following traumatic brain injury.
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Metabolic disorders on cognitive dysfunction after traumatic brain injury: Trends in Endocrinology & Metabolism
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PDF) Traumatic Injury to the Brain and Endocrine Evaluation of the Anterior Pituitary a Year After the Event (The TRIBE Study)
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