Zone of the Enders: Dolores, i (TV Series 2001) - IMDb

Z.O.E Dolores, i: Com Tesshô Genda, Travis Dean, Britt Baker, Houko Kuwashima. James Links is a 49-year-old space trucker anxious to return to Earth and reunite with his estranged children Leon and Noel. While transporting some goods to Earth, he stumbles upon "Dolores," a highly-advanced Orbital Frame with an A.I. of unknown origin. The situation gets more complicated when inspectors aboard his ship are murdered and James is wanted for the crime. Making matters worse is that Leon and Noel are also wanted by the authorities simply because they are James' children. Now as fugitives running from the law, James, Leon and Noel must go by any means necessary to make sure Dolores does not fall into the wrong hands, as she holds the key to the whereabouts of James' wife, Dr. Rachel Links.

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