Using origami DNA to trap large viruses

A team of researchers from the Technical University of Munich and the University of Regensburg, both in Germany, has found that it is possible to build origami DNA structures that can be used to trap large viruses. In their paper published in the journal Cell Reports Physical Science, the group describes how they built their structures and how well they worked when tested.

Origami DNA Traps Could Keep Large Viruses From Infecting Cells: by engineering structures out of DNA, scientists could potentially prevent larger viruses, like coronaviruses and influenza viruses, from interacting with cells.

DNA origami shells and functionalization with HS derivatives. (A) A

Programming Dynamic Assembly of Viral Proteins with DNA Origami

DNA Origami Inside-Out Viruses

Programmable icosahedral shell system for virus trapping

Programmable icosahedral shell system for virus trapping

Nano traps' to lock up and neutralize viruses •

Neutralising viruses with DNA origami traps

DNA origami nanoturbine sets new horizon for nanomotors

DNA origami traps for large viruses - ScienceDirect

ISNSCE – International Society for Nanoscale Science, Computation and Engineering

Isothermal self-assembly of multicomponent and evolutive DNA nanostructures

Multiple viruses and VLPs trapped in HS-modified O, T1, and T3 shells.

DNA origami traps for large viruses - ScienceDirect

The virus trap