Single-dose therapeutic interfering particle lowers SARS-CoV-2 pathogenesis and shedding among hamsters

Researchers reported that a single-dose therapeutic interfering particle (TIP) lowers SARS-CoV-2 pathogenesis and shedding among hamsters.

Pathogens, Free Full-Text

Frontiers Experimental Models of COVID-19

A single-administration therapeutic interfering particle reduces SARS-CoV-2 viral shedding and pathogenesis in hamsters

Inhibitors of SARS-CoV-2 Entry: Current and Future Opportunities

Frontiers A 21st Century Evil: Immunopathology and New Therapies of COVID-19

Organoids to Remodel SARS-CoV-2 Research: Updates, Limitations and Perspectives

A rational roadmap for SARS‐CoV‐2/COVID‐19 pharmacotherapeutic research and development: IUPHAR Review 29 - Alexander - 2020 - British Journal of Pharmacology - Wiley Online Library

Mechanisms of SARS-CoV-2-induced lung vascular disease: potential role of complement - Kurt R. Stenmark, Maria G. Frid, Evgenia Gerasimovskaya, Hui Zhang, Mary K. McCarthy, Joshua M. Thurman, Thomas E. Morrison, 2021

Pulmonary infection by SARS-CoV-2 induces senescence accompanied by an inflammatory phenotype in severe COVID-19: possible implications for viral mutagenesis

Absolute quantitation of individual SARS-CoV-2 RNA molecules provides a new paradigm for infection dynamics and variant differences

TEMPOL inhibits SARS-CoV-2 replication and development of lung disease in the Syrian hamster model - ScienceDirect

Pathogens, Free Full-Text

A single intranasal or intramuscular immunization with chimpanzee adenovirus-vectored SARS-CoV-2 vaccine protects against pneumonia in hamsters - ScienceDirect

Synthetic defective interfering viruses. (A) Three portions of the wild

COVID-19 convalescent plasma and randomized clinical trials: explaining conflicting outcomes and finding signals of efficacy