Nutrients, Free Full-Text
Por um escritor misterioso
Last updated 07 julho 2024
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Cow’s milk protein allergy (CMPA) is associated with dysbiosis of the infant gut microbiome, with allergic and immune development implications. Studies show benefits of combining synbiotics with hypoallergenic formulae, although evidence has never been systematically examined. This review identified seven publications of four randomised controlled trials comparing an amino acid formula (AAF) with an AAF containing synbiotics (AAF-Syn) in infants with CMPA (mean age 8.6 months; 68% male, mean intervention 27.3 weeks, n = 410). AAF and AAF-Syn were equally effective in managing allergic symptoms and promoting normal growth. Compared to AAF, significantly fewer infants fed AAF-Syn had infections (OR 0.35 (95% CI 0.19–0.67), p = 0.001). Overall medication use, including antibacterials and antifectives, was lower among infants fed AAF-Syn. Significantly fewer infants had hospital admissions with AAF-Syn compared to AAF (8.8% vs. 20.2%, p = 0.036; 56% reduction), leading to potential cost savings per infant of £164.05–£338.77. AAF-Syn was associated with increased bifidobacteria (difference in means 31.75, 95% CI 26.04–37.45, p < 0.0001); reduced Eubacterium rectale and Clostridium coccoides (difference in means −19.06, 95% CI −23.15 to −14.97, p < 0.0001); and reduced microbial diversity (p < 0.05), similar to that described in healthy breastfed infants, and may be associated with the improved clinical outcomes described. This review provides evidence that suggests combining synbiotics with AAF produces clinical benefits with potential economic implications.
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Nutrients, Free Full-Text
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Nutrients, Free Full-Text
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Assar V 5.1 Ea Get File - Colaboratory
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Nutrients, Free Full-Text
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Nutrients, Free Full-Text
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Healthy Eating Plate, The Nutrition Source
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Nutrients, Free Full-Text
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21.09.2020: “Efeitos imunomoduladores da vitamina D em infecções
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Eating like a God - Whole Food & Nutrient Synergy - Sample
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British Journal of Nutrition
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Player Resource Consortium V3.6 Alpha - Colaboratory
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Nutrients, Free Full-Text
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Nutrients, Free Full-Text
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Impact of Varying Dosages of Fish Oil on Recovery and Soreness
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Home Page: The American Journal of Clinical Nutrition
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