Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization
Por um escritor misterioso
Last updated 18 fevereiro 2025
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![Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization](https://www.researchgate.net/publication/338212439/figure/fig2/AS:864345072349190@1583087332582/Continued-e-clcn7-th-th-and-clcn7-del4-del4-larvae-expressing-cdh17GFP-green.png)
Continued) (e) clcn7 þ/þ and clcn7 del4/del4 larvae expressing
Cystine, C6H12N2O4S2
![Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization](https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41467-023-39261-3/MediaObjects/41467_2023_39261_Fig1_HTML.png)
From molecules and cells to organisms
![Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41467-023-39261-3/MediaObjects/41467_2023_39261_Fig1_HTML.png)
Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization
![Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization](https://www.researchgate.net/publication/372368274/figure/fig1/AS:11431281174850817@1689389362215/Cystine-storage-diverts-differentiation-towards-growth-and-proliferation-a-Cystine-levels_Q320.jpg)
PDF) Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization
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Dietary supplementation of cystinotic mice by lysine inhibits the megalin pathway and decreases kidney cystine content
![Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization](https://www.researchgate.net/publication/358509261/figure/fig5/AS:1140231709433857@1648863832948/Proximal-tubule-cells-derived-from-Ctns--rat-kidneys-recapitulate-key-features-of.jpg)
Proximal tubule cells derived from Ctns −/− rat kidneys recapitulate
![Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization](https://www.researchgate.net/publication/358509261/figure/fig1/AS:1140231709425665@1648863832837/Generation-and-validation-of-the-Ctns-knockout-rat-model-A-CRISPR-Cas9-induced-a-12-bp.jpg)
Generation and validation of the Ctns knockout rat model. (A)
![Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization](https://www.itinerare.uzh.ch/dam/jcr:de3b9b9a-10a2-4fd9-bf5a-5e7ea7a32ac2/Slide1.jpg)
URPP ITINERARE, URPP ITINERARE
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AI Helps Discover Suitable Drugs for a Serious Metabolic Disease
Cystine, C6H12N2O4S2
![Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization](https://www.researchgate.net/publication/281143669/figure/fig12/AS:667206459338761@1536085824323/Fate-Mapping-of-Sox9-Cell-Descendants-Shows-Extensive-Contribution-to-the-Ureteric-and.jpg)
Fate Mapping of Sox9 + Cell Descendants Shows Extensive Contribution to
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