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Last updated 16 julho 2024
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Sphinganine-analog mycotoxins (SAMs) including fumonisins and A. alternata f. sp. Lycopersici (AAL) toxins are a group of related mycotoxins produced by plant pathogenic fungi in the Fusarium genus and in Alternaria alternata f. sp. Lycopersici, respectively. SAMs have shown diverse cytotoxicity and phytotoxicity, causing adverse impacts on plants, animals, and humans, and are a destructive force to crop production worldwide. This review summarizes the structural diversity of SAMs and encapsulates the relationships between their structures and biological activities. The toxicity of SAMs on plants and animals is mainly attributed to their inhibitory activity against the ceramide biosynthesis enzyme, influencing the sphingolipid metabolism and causing programmed cell death. We also reviewed the detoxification methods against SAMs and how plants develop resistance to SAMs. Genetic and evolutionary analyses revealed that the FUM (fumonisins biosynthetic) gene cluster was responsible for fumonisin biosynthesis in Fusarium spp. Sequence comparisons among species within the genus Fusarium suggested that mutations and multiple horizontal gene transfers involving the FUM gene cluster were responsible for the interspecific difference in fumonisin synthesis. We finish by describing methods for monitoring and quantifying SAMs in food and agricultural products.
Loads of Free, Full-Text Nursing Journal Articles for Nurses Week [Six Days Only] – Nursetopia
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Just Another Foundry – JAF Johannes
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Health Effects of Trace Metals in Electronic Cigarette Aerosols—a Systematic Review
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The Fungi 1 2 3 5.1 Million Species - Colaboratory
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Boots fans can get £369-worth of free full-size premium makeup and anti-ageing skincare from Bobbi Brown, Huda, Too Faced and Urban Decay - Manchester Evening News
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Gratis Open Access Publishers
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Journal of Internal Medicine - Wiley Online Library
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Processes, Free Full-Text
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Jo Font : Download For Free, View Sample Text, Rating And More On
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Toxins, Free Full-Text
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