JPM, Free Full-Text
Por um escritor misterioso
Last updated 02 julho 2024
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Asthma is a complex multifactorial and heterogeneous respiratory disease. Although genetics is a strong risk factor of asthma, external and internal exposures and their interactions with genetic factors also play important roles in the pathophysiology of asthma. Over the past decades, the application of high-throughput omics approaches has emerged and been applied to the field of asthma research for screening biomarkers such as genes, transcript, proteins, and metabolites in an unbiased fashion. Leveraging large-scale studies representative of diverse population-based omics data and integrating with clinical data has led to better profiling of asthma risk. Yet, to date, no omic-driven endotypes have been translated into clinical practice and management of asthma. In this article, we provide an overview of the current status of omics studies of asthma, namely, genomics, transcriptomics, epigenomics, proteomics, exposomics, and metabolomics. The current development of the multi-omics integrations of asthma is also briefly discussed. Biomarker discovery following multi-omics profiling could be challenging but useful for better disease phenotyping and endotyping that can translate into advances in asthma management and clinical care, ultimately leading to successful precision medicine approaches.
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JPMorgan reaps profit boost from higher interest rates
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JPM, Free Full-Text
Guide to the Markets J.P. Morgan Asset Management
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JPM, Free Full-Text
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JPM, Free Full-Text
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Ansys 17.2 License File Free Download - Colaboratory
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Notes on the Week Ahead J.P. Morgan Asset Management
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Valentines Day Games Word Search Valentines Printable Games
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Model Portfolios J.P. Morgan Asset Management
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Wise Unpacker Utility - Colaboratory
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