Diseases, Free Full-Text
Por um escritor misterioso
Last updated 15 julho 2024
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Colorectal cancer (CRC) is the third most common cancer worldwide. A diagnosis at early stages with enhanced screening methods is vital as metastases and recurrences increase mortality. The aim of this study was to analyze the tumor markers CEA and CA19-9 combined in correlation with diagnostics and prognosis. Therefore, 1487 patients with CRC who were diagnosed and treated between 2000 and 2015 at the University Hospital Ulm, Germany, were retrospectively evaluated. Overall and recurrence-free survival was analyzed in association with preoperative CEA and CA19-9 separately and combined and a multivariate analysis was performed. The 5-year overall survival was significantly shorter in patients with a CEA or CA19-9 level ≥200 compared to patients with an increased, but <200, or normal level (CEA: 69%/44%/7%; CA19-9: 66%/38%/8%). Patients with both tumor markers increased also showed a remarkably shorter 5-year survival rate (CEA+/CA19-9+: 23%). The multivariate analysis emphasizes these results (p-value < 0.0001). Patients with both tumor markers elevated had the shortest 5-year recurrence-free survival rate, followed by patients with either CEA or CA19-9 elevated (CEA-/CA19-9-: 79%; CEA+/CA19-9; CEA-/CA19-9+: 65%; CEA+/CA19-9+: 44%). In conclusion, measuring CEA and CA19-9 preoperatively in CRC patients is reasonable and could be useful as a prognostic factor.
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Physical Activity and Nutrition
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Incidence of tuberculosis in HIV-infected adults on first- and second-line antiretroviral therapy in India, BMC Infectious Diseases
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Full Body Checkup in Jaipur at Low Price, Free Home Collection
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Report: Healthy Fossil Fuel Free World Means Re-Imagining New Clean Energy Future - The Global Climate and Health Alliance
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Effects of lifelong testosterone exposure on health and disease using Mendelian randomization
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Over half of known human pathogenic diseases can be aggravated by climate change
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Clinical Characteristics of Coronavirus Disease 2019 in China
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Emotions + Disease
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IJMS, Free Full-Text
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21-Gene Assay to Inform Chemotherapy Benefit in Node-Positive Breast Cancer
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Prevention of venereal diseases: the black silhouettes of a woman and a man approach each other, she from an orange ground, he standing on mauve letters VD on a red ground. Colour
Article: Monoclonal gammopathy of renal significance (MGRS) histopathologic classification, diagnostic workup, and therapeutic options (full text) - September 2019 - NJM
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Non-communicable Diseases - Types and Prevention
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