Biomedicines, Free Full-Text
Por um escritor misterioso
Last updated 16 julho 2024
![Biomedicines, Free Full-Text](https://pub.mdpi-res.com/biomedicines/biomedicines-11-01633/article_deploy/html/images/biomedicines-11-01633-ag.png?1685959184)
Infections are important factors contributing to the morbidity and mortality among elderly patients. High rates of consumption of antimicrobial agents by the elderly may result in increased risk of toxic reactions, deteriorating functions of various organs and systems and leading to the prolongation of hospital stay, admission to the intensive care unit, disability, and lethal outcome. Both safety and efficacy of antibiotics are determined by the values of their plasma concentrations, widely affected by physiologic and pathologic age-related changes specific for the elderly population. Drug absorption, distribution, metabolism, and excretion are altered in different extents depending on functional and morphological changes in the cardiovascular system, gastrointestinal tract, liver, and kidneys. Water and fat content, skeletal muscle mass, nutritional status, use of concomitant drugs are other determinants of pharmacokinetics changes observed in the elderly. The choice of a proper dosing regimen is essential to provide effective and safe antibiotic therapy in terms of attainment of certain pharmacodynamic targets. The objective of this review is to perform a structure of evidence on the age-related changes contributing to the alteration of pharmacokinetic parameters in the elderly.
![Biomedicines, Free Full-Text](https://i0.wp.com/www.mdpi.com/biomedicines/biomedicines-11-03324/article_deploy/html/images/biomedicines-11-03324-g002.png?w=1170&ssl=1)
Biomedicines, Free Full-Text
![Biomedicines, Free Full-Text](https://biomedscis.com/images/life-sciences-group.jpg)
Open Access Journal of Biomedical Science
![Biomedicines, Free Full-Text](https://www.frontiersin.org/files/Articles/626805/fcell-09-626805-HTML-r2/image_m/fcell-09-626805-g001.jpg)
Frontiers A Critical Perspective on 3D Liver Models for Drug Metabolism and Toxicology Studies
![Biomedicines, Free Full-Text](https://surveymonkey-assets.s3.amazonaws.com/survey/318600700/6fae388b-b61e-493e-98c6-0cec81e97eb2.png)
Biomedicines (ISSN 2227-9059, IF: 6.081) Questionnaire: Participate in the 10th Anniversary Online Survey Now
![Biomedicines, Free Full-Text](https://images-na.ssl-images-amazon.com/images/I/51nxs-iwlqL._AC_UL600_SR600,600_.jpg)
Biomedical Informatics: Computer by Richard W. Bulliet
![Biomedicines, Free Full-Text](https://biomedscis.com/images/pharma-group.jpg)
Open Access Journal of Biomedical Science
![Biomedicines, Free Full-Text](https://pub.mdpi-res.com/biomedicines/biomedicines-11-01200/article_deploy/html/images/biomedicines-11-01200-g001-550.jpg?1681804245)
Live Cd Pt Br Get File - Colaboratory
![Biomedicines, Free Full-Text](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41587-023-01744-5/MediaObjects/41587_2023_1744_Fig1_HTML.png)
CRISPR editing in the lung with novel lipids
![Biomedicines, Free Full-Text](https://chemistry-europe.onlinelibrary.wiley.com/cms/asset/f1f8e507-272d-4901-8e9c-1805373feaa5/cmdc202200142-fig-0007-m.jpg)
Functional Nanomaterials in Biomedicine: Current Uses and Potential Applications - Diez‐Pascual - 2022 - ChemMedChem - Wiley Online Library
![Biomedicines, Free Full-Text](https://pub.mdpi-res.com/biomedicines/biomedicines-11-00583/article_deploy/html/images/biomedicines-11-00583-ag-550.jpg?1676541808)
Crack Asd 2014 Get File - Colaboratory
Recomendado para você
-
Jogo de damas(draughts, checkers)no kurnik.org16 julho 2024
-
Chemical Kinetic Strategies for High‐Throughput Screening of Protein Aggregation Modulators - Sárkány - 2019 - Chemistry – An Asian Journal - Wiley Online Library16 julho 2024
-
La Reina de Damas en Mexico - The Checker Maven16 julho 2024
-
Baśka - Wikipedia16 julho 2024
-
Chee's Troll blog16 julho 2024
-
Association of tranexamic acid with decreased blood loss in patients undergoing laminectomy and fusion with posterior instrumentation: a systematic review and meta-analysis in: Journal of Neurosurgery: Spine Volume 36 Issue 4 (2021) Journals16 julho 2024
-
June 1851 hi-res stock photography and images - Page 9 - Alamy16 julho 2024
-
Pin on appetizers16 julho 2024
-
Draughts - Academic Kids16 julho 2024
-
Professores e Alunos - Stricto Sensu em Administração - UNINOVE16 julho 2024
você pode gostar
-
Basquetebol: Petro de Luanda vence 1.º de Agosto e conquista Taça16 julho 2024
-
Game Review: Snakesss – Gaming With Sidekicks16 julho 2024
-
Hunter X Hunter Temporada 216 julho 2024
-
Trash talking NFL superstars that never stop16 julho 2024
-
So I'm trying to download a game from g4u.to but I'm not sure where I'm supposed to click to download because when I press any of these it takes me to either16 julho 2024
-
When is the Champions League last 16 draw? Date, time, teams, live16 julho 2024
-
O que é A Lenda de Vox Machina? O que esperar?16 julho 2024
-
KonoSuba Anime Light novel Manga Aqua, Anime, fictional Character, cartoon, pixiv png16 julho 2024
-
Pin by Cheridan Landers on RH Sets !16 julho 2024
-
Dr. STONE Temporada 3: Fecha de estreno, como verla, avances y más - Crunchyroll Noticias16 julho 2024